Severe COVID wakes dormant viruses — and one of them marks long COVID
Across 1,154 hospitalized patients, nearly one in two sees a dormant chronic virus reactivate during acute COVID — herpes, cytomegalovirus, Epstein-Barr, but also the inconspicuous anelloviruses. The latter are associated, during convalescence, with the form of long COVID marked by physical disability. Association, not causation: the authors say so in black and white.
FNIP1 — when breaking a gene protects metabolism
In more than a million people, ultra-rare variants that switch off the FNIP1 gene come with a favourable lipid profile, a higher share of lean mass and less visceral fat, alongside roughly 60% lower odds of cardiometabolic disease. In mice, by contrast, switching off FNIP1 alone does nothing: it is the whole pathway that has to be cut.