Longevity & Anti-Aging
Healthy life: aging biology, cell therapies and regeneration
Overview
Study of aging mechanisms and interventions that may help prevent age-related diseases.
Impact: Prevention of age-related disease and extension of healthy life
Involved actors
Projects
Active
XPRIZE Healthspan
XPRIZE Foundation
The finalist cohort announced in August 2026 is entering coordinated clinical trials. No rejuvenating effect in humans has yet been demonstrated.
International competition assessing candidate interventions against shared criteria for muscle, cognitive and immune function.
- Coordinated clinical trials
- Muscle function
- Cognitive function
- Immune function
Roadmap: Finalist clinical trials
2030
ARPA-H — PROSPR
ARPA-H
Performer teams were selected in February 2026 to develop scores, validate biomarkers and test interventions. Clinical outcomes remain to be established.
ARPA-H research program seeking to define biomarkers and shorter trial protocols for studying health across aging.
- Aging biomarkers
- Functional measurement
- Decentralized trials
- Candidate interventions
Roadmap: Biomarker validation and trial initiation
2030+
NIH Common Fund — Cellular Senescence Network (SenNet)
NIH Common Fund
SenNet publishes atlases, data and tools to structure senescence research. It is not an anti-aging therapy.
NIH network mapping senescent cells, their states and the molecules they secrete across tissues.
- Multi-tissue atlas
- Senescence biomarkers
- Single-cell technologies
- Public data portal
Roadmap: Consolidation and publication of atlas data
2026+